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In the last three years, more than 100 miscarriages of justice have been quashed following CCRC referrals
The first step in challenging a conviction or sentence is typically applying directly to the Appeal Courts. If that has been unsuccessful (or if you pleaded guilty in a Magistrates' Court), you can apply for a CCRC review of your case.
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Post Office / Horizon scandal

The Post Office Horizon scandal is the most widespread miscarriage of justice the CCRC has ever seen.

If you believe that you have been wrongly convicted because of problems with the Horizon computer system, you can consider challenging your conviction.